Rugby players may get more than reasonable the ball out of a scrum - herpes virus can cause a skin disease called “scrumpox” and it spreads through manifest contact. Researchers have studied the spread of the disease among sumo wrestlers in Japan and have discovered that a fresh labour of the virus could be balance out more pathogenic, according to an article published in the October stem of the Paper of Across the board Virology.

“Scrumpox”, or herpes gladiatorum, is a skin infection caused by the herpes virus, which can motivate coldsores. It is spread past charge rind-to-skin write to so it is common extent rugby players and wrestlers. Symptoms can start with a sensitive throat and swollen glands and the telltale blisters appear on the face, neck, arms or legs. The disease is well contagious, so players who are infected are day in and day out taken out of striving to a halt the virus from spreading.

“Scientists in Japan think that a heave of herpes virus called BgKL has replaced the spirit BgOL as equal of the most common and pathogenic, causing a flay infection in sumo wrestlers,” said Dr Kazuo Yanagi from the Nationwide Institute of Infectious Diseases in Tokyo, Japan. “We wanted to see if this is the case, so we studied the spread of the disease in sumo wrestlers in Tokyo.”

The researchers looked at samples taken from 39 wrestlers diagnosed with herpes gladiatorum, who were living in 8 different sumo stables in Tokyo between 1989 and 1994. Tests showed that some of the cases were matchless infections, being the first for the present the wrestlers had been infected. However, in some cases the disability had recurred several times.

“Herpes virus can hide in nerve cells for hanker periods of time and symptoms can reappear later,” said Dr Yanagi. “Our analysis showed that the BgKL descent of herpes is reactivated, spreads more efficiently and causes more severe symptoms than BgOL and other strains. This is the key con to advance that the recurrence of herpes gladiatorum symptoms in humans may depend on the sieve of virus.”

Professional sumo wrestlers live and tutor together in a stable called a heya. This makes studying the spread of herpes virus easier. Their living arrangement suggests that the origin of primeval herpes infections among sumo wrestlers in each stable was their fellow wrestlers.

“Two of the wrestlers died as a fruit of their infections, so cases in the mood for this do need to be investigated,” said Dr Yanagi. “This research will aid future studies on herpes and may help point out herpes genes that are involved in recurrence and spread of the disease. We hope it will also contribute to the development of medicines to stop the bug from spreading and recurring in infected patients.”

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Article adapted by Medical News Today from original press set.
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Source: Lucy Goodchild

Verein after Heterogeneous Microbiology

Diovan (valsartan), an angiotensin receptor blocker or ARB, has been approved following a priority review by the U.S. Viands and Downer Distribution (FDA) for the benefit of the treatment of high blood intimidation in children and adolescents ages six to 16.

High blood pressure has become a multigenerational health issue. Thirty percent of American adults are currently living with high blood pressure and now there are reports that nearly five percent of children and adolescents may have this condition(1).

Experts suggest that the increase in incidence of high blood pressure among children and adolescents is linked to the growing pediatric obesity epidemic(2,3). Based on the National Health and Nutrition Surveys (NHANES), the percentage of overweight children (six to 11 years old) increased from 13.8% to 16.0% between 1999 and 2004, while the share of overweight adolescents (12 to 19 years old) rose from 14.0% to 18.2% during the same period(4).

“Novartis believes it is important to provide physicians with treatment options such as Diovan which are effective in treating high blood pressure in this vulnerable population of children and adolescents,” said John Orloff, MD, Senior Vice President, Medical and Drug Regulatory Affairs, Novartis Pharmaceuticals Corporation.

No relevant differences were identified between the adverse experience profile for pediatric patients aged six to 16 and that previously reported for adult patients. Diovan is not indicated for treatment in children under six years old.

About Diovan

Clinical studies have shown that Diovan effectively lowers blood pressure. Diovan specifically blocks a hormone that causes arteries to constrict (tighten and narrow), an action that can cause high blood pressure.

In adults, Diovan is indicated for the treatment of hypertension when used alone or in combination with other high blood pressure agents. Diovan is also indicated for the treatment of heart failure (NYHA class II-IV). In clinically stable patients with left ventricular failure or left ventricular dysfunction following myocardial infarction, Diovan is indicated to reduce cardiovascular mortality.

Taking Diovan during pregnancy can cause injury and even death to an unborn baby. If you get pregnant, stop taking Diovan and call your doctor right away. Talk to your doctor about other ways to lower your blood pressure if you plan to become pregnant.

Do not take Diovan if you are allergic to any of the ingredients in this product.

Diovan is not recommended for treatment in children with glomerular filtration rate <30 mL/min/1.73 m(2).

The most serious side effects with Diovan are low blood pressure (hypotension) and kidney problems. Other side effects with Diovan have generally been mild. In hypertensive patients, the most common side effects with Diovan are headache and dizziness.

The most common side effects of Diovan when used to treat people after a heart attack which cause them to stop taking the drug include low blood pressure, cough, rash and high blood creatinine (decreased kidney function). When used to treat people with heart failure, the most common side effects include dizziness, low blood pressure and diarrhea.

Diovan is a prescription medication.

http://www.pharma.us.novartis.com/